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目的探讨通过MRI评估原发性肝癌化疗栓塞手术效果。方法选取2014年8月至2016年6月间新疆医科大学第二附属医院收治的68例原发性肝癌患者。所有患者经导管肝动脉化疗栓塞术前及术后1个月分别进行磁共振成像(MRI)检查,术后3个月行MRI增强扫描检查。根据实体瘤疗效评价标准将患者分为进展组与未进展组,比较两组患者的MRI图像特征。结果导管肝动脉化疗栓塞术(TACE)后,患者中有腹腔积液2例,肝门区胆管扩张3例,边缘结节样强化16例。疗效评价进展48例,纳入进展组,MRI结果显示弥散加权成像(DWI)呈现低信号,T1WI呈现高信号,T2WI表现为低或偏低信号,其中2例表现为边缘不光整;未进展组的信号特点与治疗前变化不明显,边缘不光整6例。两组患者的MRI图像特征比较,差异有统计学意义(P<0.05)。结论 TACE能够有效破坏肿瘤活性,可作为肿瘤根治性切除术的辅助和补充。
Objective To evaluate the effect of chemoembolization on primary liver cancer by MRI. Methods Sixty-eight patients with primary liver cancer who were admitted to the Second Affiliated Hospital of Xinjiang Medical University between August 2014 and June 2016 were selected. All patients underwent magnetic resonance imaging (MRI) before transcatheter arterial chemoembolization and at 1 month after surgery. MRI enhanced scanning was performed 3 months after the operation. The patients were divided into progressive group and non-progressive group based on the evaluation criteria of solid tumor efficacy. The MRI features of the two groups were compared. Results After transcatheter arterial chemoembolization (TACE), there were 2 cases of ascites, 3 cases of hilar dilatation in hilar region, and 16 cases of border nodular enhancement. Forty-eight cases were included in the progress group. The results of MRI showed low signal intensity in DWI, high signal in T1WI, low or low signal in T2WI, and 2 cases showed edge irregularity. In non-progressive group Signal characteristics and changes before treatment is not obvious, not only the edge of the entire 6 cases. MRI features of the two groups of patients were compared, the difference was statistically significant (P <0.05). Conclusion TACE can effectively destroy the tumor activity and can be used as a supplement and supplement for radical resection of tumor.