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目的:分析院内剖宫产患者围手术期抗菌药物应用情况,为临床合理用药提供依据。方法:采用回顾性采用Excel2003版软件对2006年9—11月份233例剖宫产患者抗菌药物应用情况进行统计分析。结果:97.85%的患者围手术期使用了抗菌药物,使用频率最高的药物为青霉素和头孢拉定;49.36%的患者在术前2h用药,85.41%的患者术后用药时间超过48h,69.10%的患者术中加用一剂抗菌药物,58.37%患者围手术期使用了3种或3种以上的抗菌药物;使用抗菌药物种数及不同的给药方案,对术后最高体温、白细胞计数及总住院天数、术后住院天数与总住院费用及西药费等指标均无显著性影响。结论:剖宫产患者围手术期抗菌药物应用存在不合理之处,按照规定应加以干预。
Objective: To analyze the application of perioperative antibacterials in cesarean section in hospital and provide the basis for clinical rational drug use. Methods: The data of 233 cases of cesarean section in September-November 2006 were analyzed retrospectively using the software of Excel2003. Results: 97.85% patients used perioperative antibiotics, penicillin and cefradin were the most frequently used drugs, 49.36% patients used medicine 2h before surgery, 85.41% patients took more than 48h after operation, 69.10% Plus one dose of antibacterial drugs, 58.37% of patients perioperative use of three or more than three kinds of antibacterial drugs; the use of antibacterial species and different dosage programs, postoperative maximum body temperature, white blood cell count and total number of hospital days , Postoperative hospital days and total hospital costs and western medicine costs and other indicators did not have a significant effect. Conclusion: There is unreasonable application of perioperative antibiotics in cesarean section patients, and should be intervened according to the regulations.