目的 观察胺碘酮对老年心动过缓伴室性早搏的临床疗效。方法选择老年心动过缓伴室性早搏患者29例, 入选者均为其它抗心律失常药物治疗效果欠佳或出现明显不良反应,口服胺碘酮4周并复查动态心电图、甲状腺功能、肝功、 胸片等。结果显示口服胺碘酮后总有效率86.20％,用药后平均心率减慢,QTc延长,不良反应发生率为20.69％。结论 胺 碘酮治疗老年心动过缓伴室性早搏相对较安全、有效。 Objective To observe the clinical effect of amiodarone on senile bradycardia with ventricular premature beats. Methods Twenty-nine elderly patients with bradycardia and premature ventricular contractions were enrolled in this study. All the patients were treated by other anti-arrhythmic drugs with poor response or obvious adverse reactions. After 4 weeks of oral administration of amiodarone and dynamic electrocardiogram, thyroid function, liver function, Chest and so on. The results showed that after oral administration of amiodarone, the total effective rate was 86.20%. After treatment, the average heart rate was slowed down and the QTc was prolonged. The incidence of adverse reactions was 20.69%. Conclusions Amiodarone is relatively safe and effective in treating bradycardia and ventricular premature beats in the elderly.