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用ＥＬＩＳＡ双抗体夹心法，检测５４例乙型肝炎患者血清可溶性肿瘤坏死因子受体（ｓＴＮＦＲ），对其中２４例重型肝炎进一步分析。结果显示：重型肝炎及慢性活动性肝炎与健康对照组有显著差异（Ｐ＜０．０１）。ｓＴＮＦＲ水平升高程度与病情呈正相关。提示，测定乙型肝炎患者血清ｓＴＮＦＲ水平，对判断病情及预测转归有一定参考价值。
Serum soluble tumor necrosis factor receptor (sTNFR) was detected in 54 patients with hepatitis B by ELISA double antibody sandwich method, and 24 cases of severe hepatitis were further analyzed. The results showed that there was significant difference between severe hepatitis and chronic active hepatitis and healthy control group (P <0.01). The level of sTNFR increased with the disease was positively correlated. Prompt determination of serum sTNFR levels in patients with hepatitis B, to determine the prognosis of the disease and predict a certain reference value.