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[目的]探讨突击量氯解磷定对急性有机磷中毒中间综合征的防治作用。[方法]随机分为两组,突击量氯解磷定组(治疗组)65例和对照组62例;两组患者中出现IMS症状的,根据是否采用突击量氯解磷定又分为甲组、乙组,采用统计学处理。[结果]治疗组阿托品用量、首次血清胆碱酯酶活性恢复﹥50%的时间、IMS发生率、死亡率等优于对照组,有明显的统计学意义(P﹤0.05);甲组自主呼吸恢复时间、脱机时间、病死率等优于乙组,有明显的统计学意义(P﹤0.05)。[结论]突击量氯解磷定对急性有机磷中毒中间综合征有防治作用。
[Objective] To investigate the prevention and treatment of the acute syndrome of organophosphate poisoning caused by the assault amount of chlorpromazine. [Methods] were randomly divided into two groups, the attack amount of chlorpheniramine group (treatment group) 65 cases and control group of 62 cases; two groups of patients with symptoms of IMS, according to whether the use of the amount of chlorpromazine is divided into a Group B, using statistical analysis. [Results] The dosage of atropine and the serum cholinesterase recovery> 50% of the time in the treatment group were superior to the control group in the incidence of IMS and mortality, with statistical significance (P <0.05). Group A spontaneous breathing Recovery time, off-line time, mortality and other advantages over the B group, with significant statistical significance (P <0.05). [Conclusion] The assault amount of chlorprohodamine has a preventive and therapeutic effect on the intermediate syndrome of acute organophosphorus poisoning.