c-ABL、c-KIT和血小板衍生因子受体-β(PDGFR-β)等酪氨酸激酶是重要的细胞生长调节因子。c-ABL是属SYC家族140 ku非受体酪氨酸激酶,推测有转录,DNA重组、修复的作用。参与控制细胞增生、分化、凋亡的信号通路。PDGFR-S构成和二聚体多肽家族,通过激活特异受体酪氨酸酶刺激增生和迁移反应。c-KIT是145 ku的酪氨酸酶跨膜受体,与 Tyrosine kinases such as c-ABL, c-KIT, and platelet-derived factor receptor-β (PDGFR-β) are important cellular growth regulators. c-ABL is a 140 ku SYC family of non-receptor tyrosine kinases, presumably transcription, DNA recombination, repair role. Participate in the control of cell proliferation, differentiation, apoptosis signaling pathway. PDGFR-S constitutes a family of dimeric polypeptides that stimulate proliferation and migration by activating specific receptor tyrosinase. c-KIT is a 145 ku tyrosinase transmembrane receptor, with