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目的 :探讨不同年龄妇女子宫颈癌的临床、病理特点及诊治方法。方法 :将子宫颈癌患者随机分为≤ 35岁与 >35岁两组 ;≤ 35岁组 137例 ,>35岁组 890例 ,分析比较两组的临床、病理及 5年生存率的差别。结果 :≤ 35岁的年轻妇女子宫颈癌症状和体征个体差异较大 ,>35岁的妇女子宫颈癌多有较明确的病灶。≤ 35岁组和 >35岁组子宫颈癌患者的病理类型构成与细胞分化分级构成差异均有显著性 (P <0 .0 1～P <0 .0 0 5 )。Ⅰ、Ⅱ期子宫颈癌患者术后复发率及远处转移率≤ 35岁组均高于 >35岁组 (P <0 .0 0 5 )。结论 :≤ 35岁的患者临床症状和体征不典型 ;腺癌发病率高 ,易发生盆腔淋巴结转移 ,预后差 ,早期病例应首选手术加化疗 ;晚期病例应采用化疗加放疗的综合性治疗
Objective: To investigate the clinical and pathological features and diagnosis and treatment of cervical cancer in women of different ages. Methods: The patients with cervical cancer were randomly divided into two groups: 35 years old and 35 years old, 137 cases ≤35 years old and 890 cases aged> 35 years old. The differences of clinical, pathological and 5-year survival rates were analyzed. Results: Young women ≤35 years of cervical cancer symptoms and signs of individual differences, more than 35-year-old woman with cervical cancer more clear lesions. The pathological type constitution and cell differentiation grade of cervical cancer patients ≤35 years and> 35 years old had significant differences (P <0.01 ~ P <0.05). The recurrence rate and distant metastasis rate of patients with stage Ⅰ and Ⅱ cervical cancer were all higher than those of 35 or older than 35 years old (P <0.05). Conclusions: The clinical symptoms and signs are not typical in patients ≤35 years old. The incidence of adenocarcinoma is high, and pelvic lymph node metastasis is easy to occur. The prognosis is poor. In the early stage, surgery and chemotherapy should be the first choice. Chemotherapy combined with radiotherapy should be used in advanced stage