新生儿硬肿症是围产期新生儿的常见病之一,病死率高达40～50％。1971年1月至1990年12月我科收治硬肿症228例,对其病因及防治措施探讨如下。 1 临床资料 1.1 一般资料 男185例,女43例,男女之比为4.3:1。7天以内发病者165例,占72.4％,其中3天以内发病者117例,占51.3％。早产儿77例(33.8％),双胎10例(4.4％),过期产1例(0.4％), Neonatal sclera is one of the common diseases of perinatal newborns, the mortality rate as high as 40 to 50%. From January 1971 to December 1990, 228 cases of scleroderma were treated in our department. The etiology and prevention measures were explored as follows. 1 Clinical data 1.1 General information 185 males and 43 females, male to female ratio of 4.3: 1.7 days incidence of 165 cases, accounting for 72.4%, of which 117 cases of onset within 3 days, accounting for 51.3%. Premature children 77 cases (33.8%), twins 10 cases (4.4%), expired in 1 case (0.4%),