孢子丝菌病和芽生菌病都是由双相真菌引起的深部真菌感染。皮肤孢子丝菌病比较常见。芽生菌病主要是系统感染,皮肤受累较少。本文首次报导孢子丝菌病和芽生菌病在同一损害内并发的病例。患者男21岁,体健,菲律宾人。发现顽固性干咳数周,约8周后在双面颊各出现一个结节。几周内结节逐渐长大,不痛不痒不出血。用双氯青霉素治疗咳嗽无效。大约3年前移居威斯康辛的一个乡镇。病前数周曾到威斯康辛北部猎鹿。否认与植物及蔬菜有损伤性接触,亦无宠物及其它动物接触史。体检:不发热,左上肺少许啰音,淋巴结未触及。鼻旁面颊对称分布一个1 cm大小的疣 Sporotrichosis and blastomycosis are both deep fungal infections caused by biphasic fungi. Sporotrichosis skin is more common. Blastomycosis is mainly a systemic infection, less skin involvement. This is the first report of concomitant lesions of sporotrichosis and blastomycosis in the same case. Male patient 21 years old, healthy, Filipino. Found stubborn dry cough for several weeks, about 8 weeks after the emergence of a nodule on both cheeks. Nodules gradually grow up in a few weeks, itching does not bleed. Dicloxacillin treatment of cough is invalid. About 3 years ago moved to a township in Wisconsin. A few weeks before the disease went to hunting deer in northern Wisconsin. Denied any harmful contact with plants and vegetables and no history of contact with pets or other animals. Physical examination: no fever, a little rales in the left upper lung, lymph nodes not touched. Nasal cheeks symmetrically distribute a 1 cm-sized wart