T lymphocyte apoptosis induced by CD8ε chimera

来源 :Chinese Science Bulletin | 被引量 : 0次 | 上传用户:lyling0411
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THE T cell repertoire is characterized by an extremely diverse population of different surface receptors (TCR) which participates in highly specific responses to a large number of different antigens and mediate antigen stimulation signals. Variable heterodimers of TCR α/β and γ/δ receptors are associated with invariable CD3γ, δ, ε and ζ proteins, thus forming the TCR/CD3 complex. CD3ε plays an important role in the initiation of TCR resembling and signfal transduction among the octopeptide chains. Stimulation by anti-CD3ε monoclonal antibody THE T cell repertoire is characterized by an extremely diverse population of different surface receptors (TCR) which participates in highly specific responses to a large number of different antigens and mediate antigen stimulation signals. Variable heterodimers of TCR α / β and γ / δ receptors are associated with invariable CD3γ, δ, ε and ζ proteins, thus forming the TCR / CD3 complex. CD3ε plays an important role in the initiation of TCR resembling and signaling in among the octopeptide chains. Stimulation by anti-CD3ε monoclonal antibody
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