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目的:观察宫颈上皮内瘤变(CIN)患者宫颈电环切除术(LEEP)后加妇乐油纱外敷的临床疗效,评价妇乐油纱促进LEEP后整体康复的增效作用,初步探讨其作用机理。方法:将符合LEEP适应症CINⅠ～Ⅱ患者76例随机分为2组各38例,对照组采用LEEP治疗,术后口服头孢拉定胶囊;治疗组采用LEEP加妇乐油纱外敷治疗,术后口服头孢拉定胶囊。观察比较2组患者治疗前后中医证候积分、阴道出血量、出血时间、排液量、排液时间、创面愈合时间等情况。结果:治疗组治疗前后中医证候积分、阴道出血量、出血时间、排液量、排液时间、创面愈合时间等疗效均优于对照组,2组比较,差异均有显著性意义(P<0.05);总有效率治疗组为100%,对照组为81.58%,2组比较,差异有显著性意义(P<0.05)。结论:CINⅠ～Ⅱ患者于LEEP后予妇乐油纱外敷治疗,可加快宫颈创面的愈合、减少和杜绝术后阴道排液、出血、粘连、疤痕等并发症的形成,有效改善中医证候,提高患者生活质量,达到整体快速康复的目的。
OBJECTIVE: To observe the curative effect of external application of marijuana gauze after cervical ring electrosurgical excision (LEEP) in cervical intraepithelial neoplasia (CIN) and to evaluate the synergistic effect of marijuana gauze in promoting overall recovery after LEEP, and to investigate its effect mechanism. Methods: 76 patients with CINⅠ ~ Ⅱ who meet the LEEP indications were randomly divided into two groups of 38 cases. The control group was treated with LEEP and cefradine capsules were given after operation. The patients in the treatment group were treated with LEEP and Calendula gauze. Postoperative oral cephradine capsule. The TCM syndrome scores, vaginal bleeding volume, bleeding time, drainage volume, drainage time and wound healing time before and after treatment were observed and compared between the two groups. Results: Before and after treatment, the TCM syndrome score, vaginal bleeding volume, bleeding time, fluid volume, drainage time and wound healing time were all better in the treatment group than in the control group. There was significant difference between the two groups (P < 0.05). The total effective rate was 100% in the treatment group and 81.58% in the control group. There was significant difference between the two groups (P <0.05). CONCLUSION: External application of Cynomorium oxyinatus to CINⅠ ~ Ⅱ patients after LEEP can expedite the healing of cervical wounds and reduce and eliminate the formation of postoperative vaginal discharge, hemorrhage, adhesions, scarring and other complications, and effectively improve TCM syndromes, Improve patient quality of life, to achieve the purpose of overall rapid recovery.