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目的:研究分析中西医结合治疗过敏性紫癜和预防肾损害的临床效果。方法:选取2013年11月至2015年11月通许县中医院院收治的过敏性紫癜患者92例,随机分为两组,各46例。对照组采用常规西医治疗,观察组给予中西医结合治疗。对比两组临床症状消失时间、住院时间、治疗前后血清β2微球蛋白(β2–MG)和血清免疫球蛋白指标情况。结果:观察组腹痛消失时间、紫癜消失时间、关节肿痛消失时间、住院时间均短于对照组,差异具有统计学意义(P<0.05);观察组治疗后β2–MG、血清免疫球蛋白A(Ig A)和血清免疫球蛋白E(Ig E)指标均低于对照组,差异具有统计学意义(P<0.05)。结论:中西医结合治疗过敏性紫癜效果显著,可明显缓解患者临床症状,预防肾损害,促进患者身体早日恢复。
Objective: To study and analyze the clinical effect of combining traditional Chinese and western medicine in the treatment of Henoch-Schonlein purpura and preventing renal damage. Methods: 92 patients with Henoch-Schonlein purpura admitted to Tongxu Hospital of Traditional Chinese Medicine from November 2013 to November 2015 were randomly divided into two groups of 46 patients. Control group using conventional Western medicine, observation group given Integrative Medicine. The disappearance time, length of hospital stay, serum β2 microglobulin (β2-MG) and serum immunoglobulin index before and after treatment were compared between the two groups. Results: The disappearance time of abdominal pain, the disappearance of purpura, the disappearance of joint swelling and the duration of hospital stay in the observation group were all significantly shorter than those in the control group (P <0.05). The levels of β2-MG, serum immunoglobulin A (Ig A) and serum immunoglobulin E (Ig E) were lower than the control group, the difference was statistically significant (P <0.05). Conclusion: Integrative treatment of allergic purpura significantly, can significantly alleviate the clinical symptoms, prevent renal damage and promote early recovery of patients.