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本文报告了65例生育男性、125例不育男性及64例妻子流产男性精浆及精子表面唾液酸含量。结果精子表面唾液酸含量分别为24.03±7.13μg/ml、15.08±8.21μg/ml及15.11±9.40μg/ml,不育及妻子流产男性与生育男性比较有显著性差异(P<0.001),提示精子表面唾液酸含量的降低可导致男性不育。附睾明显结节患者与无附睾结节者精浆唾液酸含量分别为130.92±21.72mg/ml和144.33±26.09mg/ml,两者有显著性差异(P<0.05),提示精浆唾液酸含量可作为附睾上皮功能的一个监测指标。本研究同时还观察到精浆唾液酸含量与精子密度成正相关,而精子表面唾液酸含量与精子质量成正相关。
This article reports the sialic acid content of seminal plasma and sperm from 65 infertile men, 125 infertile men and 64 wives. Results The sialic acid contents of sperm were 24.03 ± 7.13μg / ml, 15.08 ± 8.21μg / ml and 15.11 ± 9.40μg / ml, respectively. There was a significant difference (P <0.001) between male and female infertility and wives miscarriage Reduced sialic acid levels on the sperm surface can lead to male infertility. Sperm acid content of seminal plasma of patients with obvious epididymal nodules and no epididymal nodules were 130.92 ± 21.72mg / ml and 144.33 ± 26.09mg / ml respectively, there was a significant difference between the two (P <0.05), suggesting that sperm acid content Can be used as a monitor of epididymal epithelial function. The study also observed that sperm acid content of sperm and sperm density is positively correlated, while sperm sialic acid content and sperm quality is positively correlated.