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恶性疟原虫感染时,可发现可溶性抗原及相应的抗体,因此使之有可能形成循环免疫复合物(CIC)。为研究凶险型恶性疟时的 CIC,并探讨其在重症恶性疟中的免疫病理学作用,作者观察9例凶险型恶性疟和23例普通型恶性疟患者的冷球蛋白、CIC、总溶血性补体和补体各成份。这32例确诊的恶性疟患者均新近来自流行区,并且从未接受过任何化学预防。观察结果如下:9例凶险型患者均测到冷球蛋白,均属 IgG 和IgM 型,在疾病的第11～16天内其含量达高峰;而
When Plasmodium falciparum infects, soluble antigens and corresponding antibodies are found, thus making it possible to form a circulating immune complex (CIC). In order to study the CIC of dangerous falciparum malaria and its immunopathological role in severe falciparum malaria, we observed the effects of cryoglobulins, CIC, total hemolytic Complement and complement components. The 32 confirmed cases of falciparum malaria have recently come from endemic areas and have never received any chemical prophylaxis. Observations are as follows: 9 cases of dangerous patients were measured cryoglobulins, are IgG and IgM type, the disease in the first 11 to 16 days its content peaked; and