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对中度高原地区（海拔２２６０ｍ）肺心病患者血中丙二醛（ＭＤＡ）的含量及超氧化物歧化酶（ＳＯＤ）的活性进行了测定，并与正常同龄人作对照。结果显示：肺心病患者血中ＭＤＡ含量明显增高（Ｐ＜０．０１），ＳＯＤ活性明显降低，（Ｐ＜０．０１）。提示中度高原地区肺心病患者体内存在着自由基代谢失衡。
The content of malondialdehyde (MDA) and the activity of superoxide dismutase (SOD) in the blood of patients with cor pulmonale at moderate altitude (2260 m above sea level) were measured and compared with normal peers. The results showed that the content of MDA in blood of patients with pulmonary heart disease was significantly increased (P <0.01), and the activity of SOD was significantly decreased (P <0.01). Prompted the presence of free radical metabolism imbalance in patients with pulmonary heart disease in moderate highland.