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目的探讨贵州省预防梅毒母婴传播的效果。方法随机抽取26个县(市、区),回顾性分析2012-2014年孕产妇中梅毒检测、梅毒感染孕产妇和所生儿童的抗梅毒治疗及干预结局。结果 2012-2014年,26个抽样县孕产妇梅毒检测率、确诊梅毒感染孕产妇数及阳性率分别从87.32%、255人、1.62‰增加至95.62%、426人、2.42‰(P<0.001);梅毒感染孕产妇规范治疗率及所生婴儿预防性治疗率从30.43%、70.60%增加至37.94%、83.30%(P<0.05);不良妊娠结局发生率和梅毒母婴传播率从7.84%、6.24%下降至6.10%、4.77%(P>0.05)。结论预防梅毒母婴传播效果显著,但尚需加强对薄弱环节的研究。
Objective To explore the effect of preventing mother-to-child transmission of syphilis in Guizhou Province. Methods Twenty-six counties (cities and districts) were randomly selected. The anti-syphilis treatment and intervention outcomes of syphilis testing, syphilis-infected pregnant women and children born during 2012-2014 were analyzed retrospectively. Results In 2012-2014, the detection rate of maternal syphilis and the number of confirmed pregnant women with syphilis in 26 sample counties increased from 87.32%, 255 and 1.62 ‰ to 95.62%, 426 and 2.42 ‰, respectively (P <0.001) ; The standard treatment rate of pregnant women with syphilis infection and the prophylactic treatment rate of infants increased from 30.43% and 70.60% to 37.94% and 83.30% respectively (P <0.05); the incidence of adverse pregnancy outcomes and syphilis were 7.84% 6.24% to 6.10%, 4.77% (P> 0.05). Conclusion The prevention of mother-to-child transmission of syphilis is significant, but research on the weak links needs to be strengthened.