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目的探讨围绝经期妇女雌激素、血脂及心血管功能指标变化情况。方法检测并比较绝经前期妇女36例、围绝经期妇女48例雌激素、血脂、心率、血压、心电图及主动脉突出等情况。结果围绝经期组血清总胆固醇TC、甘油三酯TG、低密度脂蛋白胆固醇LDL-C水平均有显著提高(P<0.05),而高密度脂蛋白胆固醇HDL-C浓度有下降(P<0.05);X射线主动脉突出发生率、心电图异常率均显著高于绝经前期组(χ2=5.60,P<0.05;χ2=6.42,P<0.05)。结论定期检测围绝经期妇女血脂、心功能检查并进行早期干预对预防围绝经期妇女心血管病变具有重要意义。
Objective To investigate the changes of estrogen, blood lipid and cardiovascular function in perimenopausal women. Methods 36 cases of premenopausal women and 48 cases of perimenopausal women were detected and compared for estrogen, blood lipid, heart rate, blood pressure, electrocardiogram and aortic protrusion. Results The levels of TC, TG and LDL-C in perimenopausal group were significantly increased (P <0.05), while HDL-C concentrations were decreased (P <0.05 ). The incidence of X-ray aortic protrusion and electrocardiogram abnormalities were significantly higher than those in the premenopausal group (χ2 = 5.60, P <0.05; χ2 = 6.42, P <0.05). Conclusions It is of great importance to detect peri - menopausal women ’s blood lipids, cardiac function and early intervention to prevent cardiovascular disease in perimenopausal women.