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毒K与氨酰心安联用,增加心肌的收缩力,增强心脏的舒张功能,降低氧耗,是治疗冠心病伴心衰的好办法之一。一、对象和方法 50例患者来自我院内科。1990年到1992年住院的冠心病病人,心功Ⅲ～Ⅳ级。随机分成二组。以随机数字单数者作为试验组,共25人,男性17例,女性8例,年龄42～74岁,平均年龄59.44岁。随机数字双数者为对照组,其中男性15例,女性10例,年龄47～84岁,平均年龄61.50岁。试验组用毒毛旋花子苷K0.125mg～0.25mg iv Qd×7天加氨酰心安12.5mg～25mg Bid po×7天。对照组用毒毛旋花子苷K0.125mg～0.25mg iv Qd×7天。疗效评定:凡用药后心功能改善一级以上者为有效,改善不到一级或恶化者为无效。注意事项:我们把急性心肌梗死48小时内作为使用毒毛旋花子苷K的禁忌症。试验期间不排除使用血管扩张剂和利尿药。
Drug K and Atenolol combined with security, increase myocardial contractility, enhance cardiac diastolic function, reduce oxygen consumption, is the treatment of coronary heart disease with heart failure is a good way. First, the object and method 50 patients from our hospital internal medicine. From 1990 to 1992 hospitalized patients with coronary heart disease, heart function Ⅲ ~ Ⅳ level. Randomly divided into two groups. A random number as the test group, a total of 25 people, 17 males and 8 females, aged 42 to 74 years, with an average age of 59.44 years. Double-digit random number as the control group, including 15 males and 10 females, aged 47 to 84 years, with an average age of 61.50 years. The test group with toxin poisonous spinosides K0.125mg ~ 0.25mg iv Qd × 7 days and valproate 12.5mg ~ 25mg Bid po × 7 days. The control group with venom spinosad K0.125mg ~ 0.25mg iv Qd × 7 days. Efficacy assessment: Where the improvement of cardiac function after treatment is effective, to improve less than one or worsen as invalid. Matters needing attention: We use contraindication to poisonous wool spinosad K within 48 hours of acute myocardial infarction. During the trial does not rule out the use of vasodilators and diuretics.