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目的:观察盐酸丁咯地尔治疗急性脑梗死的临床疗效及安全性。方法:设立盐酸丁咯地尔治疗组及低分子右旋糖酐加复方丹参对照组。治疗前后检测血液流变学及采用神经功能缺损和生活能力状态量表评分进行疗效判定。结果:治疗组总有效率90.7％,高于对照组的68.9％。治疗组血液流变学改善,神经功能缺损评分减少,与对照组比较均有显著性差异(P<0.05)。结论:盐酸丁咯地尔治疗急性脑梗死有较好疗效,副作用少而轻。
Objective: To observe the clinical efficacy and safety of buflomedil hydrochloride in the treatment of acute cerebral infarction. Methods: Buflomedil hydrochloride treatment group and low molecular dextran plus compound Salvia control group. Hemorheology was detected before and after treatment, and neurological impairment and viability status scale were used to determine the therapeutic effect. Results: The total effective rate was 90.7% in the treatment group, 68.9% higher than that in the control group. The treatment group improved the hemorheology and decreased the neurological deficit scores, which were significantly different from the control group (P <0.05). CONCLUSION: Buflomedil hydrochloride is effective in treating acute cerebral infarction with few side effects.