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以脑电图为观察指标,从临床与实验两个角度研究抗痫胶囊对癫痫异常放电的影响。结果,临床用药4周,可明显缩短癫痫患儿脑电图癫痫异常放电的累计时间,与用药前比较,P<0.05,在脑电图改善的同时,临床发作次数也相应地减少或消失;即时实验用药,可使戊四氮诱发的大白鼠脑电图阵发性棘波样改变的持续时间明显缩短,与模型对照组比较,P<0.001。
Using EEG as an observation index, the effect of anti-epileptic capsules on abnormal discharge of epilepsy was studied from both clinical and experimental points of view. As a result, 4 weeks of clinical use could significantly reduce the cumulative time of EEG epilepsy abnormal discharge in children with epilepsy. Compared with pretreatment, P<0.05, the number of clinical seizures was correspondingly decreased when EEG was improved or Disappeared; immediate experimental medication can make the pentylenetetrazol-evoked EEG brain Spike-like changes in the duration of spontaneum significantly reduced, compared with the model control group, P <0.001.