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目的探讨呼出气一氧化氮(FENO)对支气管的诊断和治疗的意义。方法检测支气管哮喘患者72例(A组,11例,哮喘完全控制;B组,30例,哮喘部分控制;C组,31例,哮喘未控制)和57例正常人(D组)FENO浓度。结果 A、B、C组FENO值分别为(33.5±22.3)ppb、(40.8±16.0)ppb和(78.0±31.5)ppb,均明显高于对照组的(17.2±11.4)ppb(P<0.01)。A、B组FENO值均低于C组(P<0.01)。结论 FENO对支气管哮喘的诊断和病情评估具有一定的临床应用价值。
Objective To investigate the significance of exhaled nitric oxide (FENO) in bronchial diagnosis and treatment. Methods 72 patients with bronchial asthma (Group A, 11 with complete control of asthma; Group B, 30 with partial asthma control; Group C with 31 uncontrolled asthma) and 57 normal controls (Group D) were enrolled in this study. Results The FENO values in groups A, B and C were (33.5 ± 22.3) ppb, (40.8 ± 16.0) ppb and (78.0 ± 31.5) ppb, respectively, which were significantly higher than those in control group (17.2 ± 11.4 ppb, . The FENO values in group A and group B were lower than those in group C (P <0.01). Conclusion FENO has some clinical value in the diagnosis and assessment of bronchial asthma.