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1987年至1989年采用前瞻性随机研究治疗鼻咽癌217例。分为二组,直线加速器(8mv-x)组107例,60Co组110例,两组年龄、性别、临床分期、治疗方法、时间剂量等因素基本相同。全组5年随访率为90%,3、5年生存率分别为60.8%和43.8%,8mv-x组分别为67.3%和49.5%,60Co组为54.5%和38.2%,8mv-x组较60Co组稍好,但无统计学差异(P>0.05).疗终颈部淋巴结残存率和原发灶复发率8mv-x组为25.6%和11.2%。60Co组为34.9%和12.7%(P>0.05)。
From 1987 to 1989, 217 cases of nasopharyngeal carcinoma were treated with prospective randomized study. There were 107 patients in the linear accelerator (8mv-x) group and 110 patients in the 60Co group. The two groups were basically the same in terms of age, sex, clinical stage, treatment method and time dosage. The overall 5-year follow-up rate was 90%, the 3-year and 5-year survival rates were 60.8% and 43.8% respectively, 67.3% and 49.5% in the 8mv-x group and 54.5% in the 60Co group % And 38.2%, 8mv-x group slightly better than 60Co group, but no statistical difference (P> 0.05). The survival rate of residual lymph nodes and the recurrence rate of primary tumors were 25.6% and 11.2% in 8mv-x group. The 60Co group was 34.9% and 12.7% (P> 0.05).