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肝脏疾病是影响人类健康的最为常见疾病之一,而各种肝脏疾病的发病机制的研究与治疗药物的筛选,在很大程度上依赖于人类肝脏疾病病理机制相似的试验动物模型的建立和应用。现在就试验性急性肝损伤动物模型的分类、造模方法、机制等进行相关的阐述。
Liver disease is one of the most common diseases affecting human health, and the pathogenesis of various liver diseases and the screening of therapeutic drugs depend largely on the establishment and application of experimental animal models with similar pathological mechanisms of human liver disease . Now on the classification of animal models of experimental acute liver injury, modeling methods, mechanisms and other related expositions.