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目的探讨高血压与高尿酸血症之间的关系及意义。方法收集高血压患者2 87例作为观察组,收集血压正常者3 1 8例作为对照组,检测两组血尿酸水平,对比分析血尿酸与高血压之间的关系。结果观察组血尿酸明显高于对照组血尿酸水平[(442.1±2 9.2)μm ol/L vs(2 1 8.3±1 8.5)μm ol/L],两组比较差异有统计学意义(P<0.0 5);高血压低危组(42 1.4±1 0.2)μm ol/L、中危组(446.9±1 1.7)μm ol/L及高危组(46 9.1±1 2.3)μm ol/L患者血尿酸均明显高于对照组(2 1 8.3±1 8.5)μm ol/L,差异有统计学意义(P<0.0 5);高血压各危险度组间比较,差异有统计学意义(P<0.0 5)。结论高血压患者血尿酸水平较血压正常者升高明显,高尿酸可能是高血压危险因素。
Objective To investigate the relationship between hypertension and hyperuricemia and its significance. Methods Two hundred and eighty-seven patients with hypertension were collected as observation group, and 381 normal-blood pressure patients were collected as control group. Blood uric acid levels were measured in both groups, and the relationship between serum uric acid and hypertension was analyzed. Results The level of serum uric acid in the observation group was significantly higher than that in the control group [(442.1 ± 2 9.2) μmol / L vs (21.3 ± 8.58) μmol / L], with significant difference between the two groups (P < 0.044). The blood levels in patients with low risk of hypertension (42.41 ± 0.2) μmol / L, moderate risk group (446.9 ± 1.7) μmol / L and high risk group (46.91 ± 1.2.3) μmol / L Uric acid were significantly higher than that of the control group (2 1 8.3 ± 1 8.5) μmol / L, the difference was statistically significant (P <0.05); There was significant difference between the two groups in risk of hypertension (P <0.0 5). Conclusion Serum uric acid levels in hypertensive patients increased significantly compared with those with normal blood pressure. Hyperuricemia may be a risk factor for hypertension.