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1985年10月9日美国密执安大学医学院急诊医学访华团的Ferrg Ragland 与协和医院内分泌科部分医生讨论了糖尿病酮症酸中毒的一些问题。近年来在美国开展了胰岛素泵的应用及向病人、家属与社会进行了糖尿病教育,但酮症酸中毒仍是内分泌急症中常遇到的情况之一,占糖尿病住院病人的14%。在酮症酸中毒发生机理中,Ragland特别强调了应激激素(即抗胰岛素作用的激素)的作用.动物试验已证明,在缺少应激激素的条件下,糖尿病动物即使缺乏胰岛素,也不会发生酮症酸中毒,如果用药物阻断这些应激激素的作用,酮症酸中毒症状可以明显减轻;而注射
October 9, 1985 Ferrg Ragland, Emergency Medical Delegation of the University of Michigan Medical School, and some of the Department of Endocrinology, Union Hospital, discussed some of the problems with diabetic ketoacidosis. In recent years, the United States launched the application of insulin pump and to patients, their families and society of diabetes education, but ketoacidosis is still often encountered in the case of endocrine emergency, accounting for 14% of diabetic inpatients. In the pathogenesis of ketoacidosis, Ragland places particular emphasis on the role of stress hormones, hormones that fight insulin, Animal tests have shown that even in the absence of stress hormones, even in the absence of insulin, diabetic animals do not Ketoacidosis occurs, if the drugs block the role of these stress hormones, ketoacidosis symptoms can be significantly reduced; and injection