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目的了解榆林市健康人群麻疹、流行性脑脊髓膜炎(流脑)和脊髓灰质炎抗体水平(脊灰),评价麻疹免疫规划工作水平,并为进一步调整免疫工作策略提供参考。方法采用随机抽样方法对榆林市7个县(区)11850名各年龄段人群采集手指末梢全血。采用酶联免疫试验试剂盒检测麻疹、流脑和脊灰抗体水平。结果 2012年榆林市7个县(区)健康人群麻疹、流脑和脊灰抗体阳性率分别为93.22%、85.72%、91.07%。不同性别麻疹、流脑和脊灰抗体水平差异均无统计学意义(P>0.05)。不同县(区)和年龄段健康人群麻疹、流脑和脊灰抗体水平存在显著差异(P<0.05)。结论榆林市健康人群麻疹、流脑和脊灰抗体可以形成有效地免疫屏障,不同县(区)与不同年龄,人群抗体阳性率可能略有差异。
Objective To understand the levels of measles, epidemic cerebrospinal meningitis (meningococcal) and poliomyelitis (polio) in healthy population in Yulin city and to evaluate the immunization planning of measles and to provide reference for further adjustment of immunization strategies. Methods A total of 11,850 people of all ages in 7 counties (districts) of Yulin City were enrolled in this study. Enzyme-linked immunosorbent assay kit was used to detect measles, meningitis and poliovirus antibody levels. Results The positive rates of measles, meningitis and poliovirus were 93.22%, 85.72% and 91.07% respectively in healthy population in 7 counties (districts) in Yulin City in 2012. There was no significant difference in antibody levels between measles, meningitis and polio in different sexes (P> 0.05). Measles, meningitis and poliovirus antibody levels in different counties (districts) and age groups were significantly different (P <0.05). Conclusion The measles, meningitis and poliovirus antibodies in healthy population of Yulin City can form an effective immune barrier. The positive rates of antibody may be slightly different in different counties (districts) and at different ages.