女性,4岁。因反复间歇性便血伴肝脾肿大2 6/12年入院。患儿生后6个月时有1次肠套,经空气灌肠复位。嗣后开始出现间歇性腹泻,大便为糊状,带少量粘液,无脓血。1年后,间歇性大便表面带有新鲜血丝,伴面色进行性苍白,腹围增大。体检:全身皮肤苍白,无黄染,营养偏差,发育良好;心率96次/分,肝肋下5cm,质中,脾肋下6cm,平脐,质硬;腹水征(一)。实验室检查:Hb65g/L,RBC2.0×10~(12)/L,WBC3 2×10~9/L,N 0.60,L 0.40。乙结肠镜检:见肛门口至深入20cm内肠粘膜面高低不平,布满息 Female, 4 years old. Due to repeated intermittent blood in the stool with hepatosplenomegaly 2 6/12 years admitted. 6 months after birth, there are 1 cases of intussusception, the air enema reduction. Subsequently began to appear intermittent diarrhea, stool as paste, with a small amount of mucus, abscess blood. 1 year later, the surface of intermittent stool with fresh bloodshot, with pale complexion, abdominal circumference increased. Physical examination: whole body pale skin, no yellow dye, nutritional deviation, well-developed; heart rate 96 beats / min, hepatic ribs 5cm, quality, spleen ribs 6cm, flat navel, hard; Laboratory tests: Hb65g / L, RBC2.0 × 10-12 / L, WBC3 2 × 10-9 / L, N 0.60, L 0.40. B colonoscopy: see the anus to the depth of 20cm intestinal mucosa uneven, full of interest