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目的探讨胃癌根治术后早期肠内营养对临床结果的影响。方法:选取我院2011年9月-2012年9月收治的60例胃癌患者进行根治手术,并随机分成对照组和观察组,每组30例。其中对照组采用比较传统的术后营养方案对患者进行治疗,观察组则早期肠内营养的针对性治疗方案,对患者按照少喝多餐和少吃多餐的饮水和进食肠内营养原则来进行营养支持。对两组患者的临床治疗结果和手术之后的营养状况、免疫指标进行对比和分析。结果:①从术后两组患者的临床结果来看,观察组患者的持续发烧时间、肛门排气的时间、术后的住院时间和体重的变化以及医疗费用都明显由于对照组患者,且两者的差异具有统计学意义(P<0.05)。②从两组患者术后3天和术后一周的营养状况来看,观察组患者术后3天和术后一周的清蛋白和前清蛋白的水平都高于对照组,且差异具有统计学意义(P<0.05)。③从两组患者术后一周的免疫功能来看,观察组患者术后一周的CD3+、CD4+、NK细胞、CD4/CD8的指标均高于对照组,且CD8+指标低于对照组,且差异具有统计学意义(P<0.05)。结论:胃癌患者在进行根治术之后,采用术后早期肠内营养的支持治疗方式能够有效改善患者的临床治疗效果,提升患者的营养状况和免疫功能。具有临床推广的意义。
Objective To investigate the effect of early enteral nutrition on clinical outcome after radical operation of gastric cancer. Methods: Sixty patients with gastric cancer admitted from September 2011 to September 2012 in our hospital underwent radical surgery and were randomly divided into control group and observation group, 30 cases in each group. The control group adopted the more traditional postoperative nutrition regimen to treat the patients, and the observation group followed the early enteral nutrition targeted treatment program. According to the principles of drinking less meals and eating less meals and eating enteral nutrition Nutritional support. On the two groups of patients with clinical treatment and nutritional status after surgery, immune indicators were compared and analyzed. Results: ① From the clinical results of two groups of patients, the duration of persistent fever, the time of anal exhaust, the length of hospital stay and body weight, and the cost of medical treatment in the observation group were significantly higher than those in the control group The difference was statistically significant (P <0.05). ②Three days after surgery and one week after surgery, the levels of albumin and prealbumin in the observation group were higher than those in the control group at 3 days and one week after surgery, and the difference was statistically significant Significance (P <0.05). ③ From the immunological function of the two groups after one week, the index of CD3 +, CD4 +, NK cells and CD4 / CD8 in the observation group was higher than that of the control group one week after operation, and the index of CD8 + was lower than that of the control group Statistical significance (P <0.05). Conclusion: After radical surgery, patients with gastric cancer treated with early postoperative enteral nutrition support therapy can effectively improve the clinical efficacy of patients and improve the patient’s nutritional status and immune function. Has clinical significance.