Liposoluble Constituents from the Flowers of Calotropis Gigantea and Their Antimicrobial Activity

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[Objectives] To study the liposoluble constituents and their antimicrobial activity from the flowers of Calotropis gigantea.[Methods]The liposoluble constituents from the flowers of Calotropis gigantea were analyzed by gas chromatography-mass spectrometry(GCMS) method and their relative content was determined by area normalization method; and their antimicrobial activity against 2 pathogens was tested by agar disc diffusion method. [Results]31 compounds were separated and identified,amounting to 85. 14% of the total constituents,27 compounds were reported for the first time in the study of the liposoluble constituents from Calotropis gigantea. The results indicated that the liposoluble constituents from the flowers of Calotropis gigantea exhibited weak antimicrobial activity against Staphylococcus aureus and Canidia albicans. [Conclusions] The research results provided scientific foundation for exploitation and utilization of Calotropis gigantea. [Objectives] To study the liposoluble constituents and their antimicrobial activity from the flowers of Calotropis gigantea. [Methods] The liposoluble constituents from the flowers of Calotropis gigantea were analyzed by gas chromatography-mass spectrometry (GCMS) method and their relative content was determined by area normalization method; and their antimicrobial activity against 2 pathogens was tested by agar disc diffusion method. [Results] 31 compounds were separated and identified, amounting to 85. 14% of the total constituents, 27 compounds were reported for the first time in the study of the liposoluble constituents from Calotropis gigantea. The results indicated that the liposoluble constituents from the flowers of Calotropis gigantea exhibited weak antimicrobial activity against Staphylococcus aureus and Canidia albicans. [Conclusions] The research results provided scientific foundation for exploitation and utilization of Calotropis gigantea.
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