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目的 探讨脑卒中后抑郁症状影响因素及护理对策.方法 对142例脑血管疾病患者采用抑郁自评量表(SDS)评估其抑郁程度,比较抑郁组与非抑郁组患者相关因素差异及护理预防对策.结果 142例脑血管疾病患者SDS评分为34～73分,平均55.69±10.25分,其中脑卒中后抑郁患者为44例(30.96％),抑郁组年龄＞70岁(68.18％)、接受教育时间≤10年(97.73％)、复发脑卒中27.27％、独居40.91％、脑力活动59.09％、经济收入较低38.64％、缺少家庭支持36.36％、护患关系一般31.82％、医疗费用自费25.00％、美国国立卫生研究院卒中量表(NIHSS)评分＞18分72.73％、未开展延伸护理68.18％高于非抑郁组(n=98)40.82％、86.73％、7.14％、4.08％、14.29％、20.41％、10.20％、10.20％、3.06％、48.98％、20.41％(P＜0.05).Logistic回归分析导致脑卒中后抑郁因素:年龄＞70岁(OR=6.167,95％CI:1.109～26.249)、接受教育时间≤10年(OR=5.825,95％CI:1.287～27.026)、NIHSS评分＞18分(OR=5.135,95％CI:1.305～22.153)、护患关系一般(OR=3.802,95％CI:1.207～19.248)、经济收入较低(OR=3.727,95％CI:0.987～21.876)、未开展延续性护理(OR=3.602,95％CI:1.409～17.345).结论 导致脑卒中后抑郁因素复杂,实施针对性护理对策有助于改善脑卒中患者心理状态,降低抑郁症状的产生.“,”Objective To explore related factors of post-stroke depression symptoms and nurse prevention measures. Methods Cerebrovascular disease patients 142 cases were assessed with self-rating depression scale (SDS). The differences of related factors between depression group and non depression group were compared. Results The SDS score of 142 patients with cerebrovascular disease was 34～73 (55.69±10.25). Among them, 44 patients (30.96％) had post-stroke depression. In the depression group, older than 70 years old 68.18％, education less than 10 years 97.73％, recurrent stroke 27.27％, lived alone 40.91％, mental activity 59.09％, low economic income 38.64％, lacked family support 36.36％, general nurse patient relationship 31.82％, medical expenses 25.00％, National Institute of Health stroke scale (NIHSS) score＞18 points 72.73％, without extended care 68.18％ were higher than non depression group 40.82％, 86.73％, 7.14％, 4.08％, 14.29％, 20.41％, 10.20％, 10.20％, 3.06％, 48.98％ and 20.41％(P＜0.05). Logistic regression analysis showed : that age＞70 years old (OR=6.167, 95％CI : 1.109～26.249), education time ≤ 10 years (OR= 5.825, 95％CI: 1.287～27.026), NIHSS score＞18 points (OR=5.135, 95％CI: 1.305～22.153), average nurse patient relationship (OR=3.802, 95％CI: 1.207～19.248) and low economic income (OR=3.727, 95％CI: 0.987～21.876), no extended care (OR=3.602, 95％CI: 1.409～17.345). Conclusion The factors leading to post-stroke depression are complex, implement targeted nursing measures to improve the psychological state of stroke patients and reduce occurrence of depressive symptoms.