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作者在高血压门诊观察了301例65岁以上高血压病人用β阻滞剂治疗的效果。其中65~69岁217例,70~74岁58例,75岁以上26例。详细地记载了病史及病情,特别注意药物的耐受性及心衰的发生率。用药方法单独用β阻滞剂者42例(14%);单独用利尿剂者51例(17%);β阻滞剂和利尿剂或合并其他治疗者193例(64%);未治疗的15例(15%)。两个最常用的β阻滞剂是metroprolol(β_1选择性)和心得安,前者每日平均剂量为189mg,后者为252mg。
The authors observed in 301 hypertensive outpatients hypertensive patients over the age of 65 with β-blocker effect. Among them, 217 cases were 65 to 69 years old, 58 cases were 70 to 74 years old and 26 cases were over 75 years old. Described in detail the history and condition, with particular attention to drug tolerance and the incidence of heart failure. Medication was given in 42 (14%) patients with beta blockers alone; in 51 (17%) patients with diuretics alone; in 193 (64%) patients with beta blockers and diuretics or in combination with other therapies; untreated 15 cases (15%). The two most commonly used beta-blockers are metroprolol (beta-1 selectivity) and propranolol, the former with an average daily dose of 189 mg and the latter 252 mg.