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作者以门诊确诊的30例慢性细菌性前列腺炎(CBP)患者作为实验组,以15例正常人作为对照组,用硫代巴比土酸法测定他们的前列腺液和血清中LPO含量;用邻苯三酚法测定其前列腺液和血清中CuZn-SOD的含量。结果发现实验组前列腺液中LPO的含量显著高于对照组(P<0.001)而CuZn-SOD的含量显著低于对照组(P<0.01),两组血清中LPO和CuZn-SOD的含量无显著性差异(P>0.05)。实验结果表明:CBP患者前列腺液中LPO和CuZn-SOD含量变化与炎症的发生发展密切相关。因而认为CBP患者前列腺液中LPO,CuZn-SOD可作为诊断、监测预后和判断疗效的有意义的辅助指标,联合应用抗菌素和SOD制剂治疗CBP,可望得到理想的疗效
Thirty patients with chronic bacterial prostatitis (CBP) diagnosed as outpatients were selected as experimental group and 15 normal persons as control group. Their LPO levels in prostatic fluid and serum were determined by thiobarbituric acid method. Determination of the contents of CuZn-SOD in prostatic fluid and serum by pyrogallol method. The results showed that the content of LPO in experimental group was significantly higher than that in control group (P <0.001), while the content of CuZn-SOD in experimental group was significantly lower than that in control group (P <0.01). LPO and CuZn-SOD There was no significant difference (P> 0.05). The experimental results show that the changes of LPO and CuZn-SOD in prostatic fluid of CBP patients are closely related to the occurrence and development of inflammation. Therefore, it is considered that LPO and CuZn-SOD in prostatic fluid of CBP patients can be used as a useful adjunct to diagnose, monitor the prognosis and judge the curative effect. Combined application of antibiotics and SOD preparation in the treatment of CBP is expected to achieve the desired effect