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应用选择性血清学调查方法对疟疾年带虫发病率(API)已降至0.1‰以下的凯里等4个县进行了流行病学评价。本法特点为疟区分层基础上的代表点调查、选择性抽样采集标本、设立年龄匹配的对照组和采用标准化间接荧光抗体试验(IFA),试图排除人群基线抗体水平不同的影响,用抽样人群疟疾抗体指数(MAT)估价当年发病率水平。结果表明:同一地区抽样人群MAI与APIs相比较,能显示病例遗漏情况及API的可靠性,从而对各县疟疾势态和监测措施质量作出较正确的估价。
Epidemiological evaluation of four counties in Carey, including the incidence of annual seroconversion of malaria (API) to 0.1 ‰, was conducted using selective serological survey. This law is characterized by surveys of representative points on a stratified basis of malaria area, selective sampling of specimens, establishment of age-matched controls and the use of standardized indirect fluorescent antibody tests (IFA) in an attempt to exclude the effects of different baseline antibody levels in the population, The malaria antibody index (MAT) of the population assesses the prevalence of the year. The results showed that compared with APIs, MAI and APIs of sampling population in the same area could show the omission of cases and the reliability of API, so as to make a more accurate assessment of the malaria situation and the quality of monitoring measures in each county.