米非司酮片联合米索前列醇片在带器宫内早孕中的应用

来源 :中国药物经济学 | 被引量 : 0次 | 上传用户:
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目的探讨米非司酮片联合米索前列醇片在带器宫内早孕中减少并发症的作用。方法选取2010年2月至2014年2月本院接诊的B超提示带器宫内妊娠6~10周要求终止妊娠且无禁忌证的63例患者,随机将其分为观察组(n=32例)与对照组(n=31例),观察组患者予以米非司酮片联合米索前列醇片后行清宫取环术,对照组患者直接行人工流产取环术,观察两组患者的取环情况。结果观察组宫颈松弛程度、取环难度、人流综合征的发生情况均优于对照组,手术时间、胚囊排出时间均短于对照组,差异有统计学意义(P均<0.05)。结论带器宫内早孕口服米非司酮片联合米索前列醇片再行清宫取环术的效果优于直接行人工流产取环术,患者宫颈松弛效果理想,清宫完全,手术时间短,易取环,人流综合征发生率低。 Objective To investigate the effect of mifepristone tablets combined with misoprostol tablets in reducing intrauterine pregnancy during pregnancy. Methods From February 2010 to February 2014, 63 patients with intrauterine pregnancy requiring intrauterine pregnancy for 6-10 weeks who received prenatal B-ultrasound and no contraindications were randomly divided into observation group (n = 32 cases) and control group (n = 31 cases). The patients in observation group were given mifepristone tablets combined with misoprostol tablets, and the patients in control group were treated by artificial abortion. The patients in two groups Take the ring situation. Results The degree of cervical relaxation, the difficulty of taking the ring and the incidence of human flow syndrome in the observation group were better than those in the control group. The operation time and the time of embryo sac delivery were all shorter than those in the control group (P <0.05). Conclusions The intrauterine pregnancy with oral mifepristone tablets combined with misoprostol tablets and recanalization is better than the direct abortion ring surgery, patients with ideal cervical relaxation, the curettage is complete, the operation time is short, easy Take the ring, the incidence of flow syndrome is low.
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