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近年来癌症发病率一直呈上升趋势,内科治疗已成为肿瘤治疗不可缺少的重要手段,然而肿瘤化疗药物会引起各种毒副作用,其中局部皮肤毒副反应也越来越常见,是肿瘤治疗过程中必须重视的问题。下面我们总结肿瘤药物外渗致皮肤坏死的治疗体会,结合文献复习相关知识。1临床资料1.1一般资料男1例,女2例,均为原发性肺癌。2例为长春新碱渗漏,1例为Vp-16渗漏,均为静脉输注过程中出现局部皮肤发红,随后肿胀,2例病人为局部发黑,另1例病人出现水疱。经积极内科治疗,完全治愈。
In recent years, the incidence of cancer has been on an upward trend, medical treatment has become an indispensable means of cancer treatment, however, chemotherapy drugs will cause a variety of toxic and side effects, including local dermal toxicity is also more and more common in the treatment of cancer Must pay attention to the problem. Below we summarize the treatment of skin necrosis caused by tumor drug extravasation, combined with the literature review related knowledge. 1 Clinical data 1.1 General information Male 1 cases, 2 females, are primary lung cancer. 2 cases of vincristine leakage, 1 case of Vp-16 leakage, are local redness occurred during the intravenous infusion, followed by swelling, two patients were partially black, the other case of patients with blisters. After active medical treatment, completely cured.