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血压得平是4-(2’-硝基苯)-2,6-二甲基-3,5-二羧甲氧基-1,4-二氢吡啶。其结构如下: 血压得平是一种钙拮抗剂,直接松弛血管平滑肌,使外周阻力降低,血压下降。作者观察此药在27例舒张压超过110mmHg的住院病人的降压作用。用安慰剂作对照,证实此药有作用快,疗效显著,持久,口服有效,副作用少等优点。口服1剂(10mg)后30分钟,从血流动力学测定证明所有病人的卧位血压平均降低21%,120分后仍降低16%,同时外周阻力
Diazepam is 4- (2’-nitrophenyl) -2,6-dimethyl-3,5-dicarboxymethoxy-1,4-dihydropyridine. Its structure is as follows: Blood pressure is flat is a calcium antagonist, vascular smooth muscle relaxation directly, so that peripheral resistance decreased, blood pressure decreased. The authors observed the antihypertensive effect of this drug in 27 inpatients with diastolic blood pressure exceeding 110 mmHg. Placebo as a control, confirmed that the drug has a rapid effect, significant effect, lasting, oral effective, less side effects and so on. Thirty minutes after the oral dose of 1 mg (10 mg), hemodynamic measurements demonstrated an average reduction of 21% in the supine blood pressure and a 16% decrease in the supine position after 120 minutes, with peripheral resistance