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目的:对比雷尼替丁和奥美拉唑对消化性溃疡(PU)的临床疗效。方法:选择我院2014年6月-2015年6月收治的70例PU患者,按照入院顺序奇偶法将其分为实验组35例及对照组35例,分别应用奥美拉唑及雷尼替丁,比较两组幽门螺杆菌(HP)根除率及临床疗效。结果:实验组HP根除率及临床总有效率分别为97.14%、97.14%,均显著高于对照组80.00%、82.86%(P<0.05)。结论:应用奥美拉唑治疗PU具有HP根除率高、临床总有效率高等优点,值得广泛应用及推广。
Objective: To compare the clinical effects of ranitidine and omeprazole on peptic ulcer (PU). Methods: Seventy patients with PU who were admitted to our hospital from June 2014 to June 2015 were divided into experimental group (35 cases) and control group (35 cases) according to the order of admission odds ratio. Omeprazole and ranitidine D, eradication rate and clinical efficacy of two groups of Helicobacter pylori (HP) were compared. Results: The eradication rate and total clinical effective rate in the experimental group were 97.14% and 97.14%, respectively, which were significantly higher than those in the control group (80.00% and 82.86%, P <0.05). Conclusion: The application of omeprazole in the treatment of PU has the advantages of high HP eradication rate and high total clinical efficiency, which is worthy of wide application and promotion.