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用中华麦饭石(CMS)制成浓度为100％的溶液,以补中益气汤和杞菊地黄汤栽化加减的中药组方其提取物浓度为1g/ml,将二者按1:1混合制成金麦健(又名“元真”)口服液,对其进行抗染色体突变、抑制腹水癌的实验研究和微生物回复突变(Ames)实验研究。Amcs实验用鼠伤寒菌株TA97、TA98、TA100及TA102,平皿掺入法,口服液按原液、1:5、1:25,1:125不同浓度投入实验,以诱变菌落数(Rt)与自发回复突变菌落数(Rc)的比值(MR)大于2且诱变作用呈现剂量效应关系时判为阳性。抗染色体突变实验用环磷酰胺作致突变剂(100mg/
The Chinese herbal medicine (CMS) was used to make a solution with a concentration of 100%. The concentration of the extract of the traditional Chinese medicine group supplemented with Buzhong Yiqi Decoction and Qiju Dihuang Decoction was 1g/ml. 1 mixed into Jinmai Jian (also known as “Yuan Zhen”) oral solution, its anti-chromosomal mutations, inhibition of experimental ascites carcinoma and microbial backmutation (Ames) experimental study. Amcs experiments using strains of Salmonella typhimurium TA97, TA98, TA100 and TA102, plate incorporation method, oral solution according to the original solution, 1:5, 1:25, 1:125 different concentrations into the experiment to mutagen colony count (Rt) and spontaneous The ratio of revertant colonies (Rc) (MR) was greater than 2 and the mutagenesis was dose-effect relationship and was judged as positive. Anti-chromosomal mutation experiment with cyclophosphamide as mutagenic agent (100mg/