目的：研究绿茶素对肿瘤的预防和辅助治疗作用。方法：采用我院从湖北绿茶提取的绿茶素（ＴＰ９１）进行了多项指标综合观察的抗肿瘤实验。瘤株为小鼠Ｓ１８０，Ｈｅｌａ细胞和ＥＡＣ。结果：（１）ＴＰ９１具明显抗癌作用，对Ｓ１８０的抑瘤率达４３６％，体外试验对Ｈｅｌａ细胞和ＥＡＣ细胞均有抑制作用，药物作用２小时后癌细胞死亡率分别为９３％和４５％；（２）给药后血液高凝状态缓解、ｃＡＭＰ升高、ＳＯＤ活性增强，外周血Ｔ淋巴细胞百分率上升、以及肿瘤间质肥大细胞数增多；（３）检出ＴＰ９１含有硒、锗等２０种元素。结论：提示绿茶素（ＴＰ９１）在肿瘤一级预防和辅助治疗中具有良好发展前景 Objective: To study the preventive and adjuvant therapeutic effects of green tea on tumors. Methods: The anti-tumor experiments with comprehensive observation of multiple indicators were carried out using the green tea extract (TP-91) extracted from Hubei green tea in our hospital. Tumor strains were mouse S180, Hela cells and EAC. Results: (1) TP91 has obvious anticancer effect, and the tumor inhibition rate of S180 is 436%. In vitro experiments have inhibitory effects on both Hela cells and EAC cells, and the cancer cell death rate after 2 hours of drug action. They were 93% and 45%, respectively; (2) Remission of hypercoagulable state, increased cAMP, increased SOD activity, increased percentage of T lymphocytes in peripheral blood, and increased number of tumor interstitial mast cells after administration; (3) Detection TP-91 contains 20 elements such as selenium and tellurium. Conclusion: It is suggested that the green teatin (TP91) has a good development prospect in primary tumor prevention and adjuvant therapy.