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  5. Long-Term Expression of Human Factor Ⅸ cDNA in Rabbits

Long-Term Expression of Human Factor Ⅸ cDNA in Rabbits

来源 :Science in China,Ser.B | 被引量 : 0次 | 上传用户：bvf
【摘 要】
：
In this study, rabbits were used as a model for gene therapy for hemophilia B, Human factor Ⅸ cDNA was transferred to cultured normal rabbit skin fibroblasts (
【作 者】
：
周洁民 邱信芳 卢大儒 陆建英 薛京伦 
【机 构】
：
InstituteofGenetics,FudanUniversity,Shanghai200433,PRC,PRC
【出 处】
：
Science in China,Ser.B
【发表日期】
：
1993年11期
【关键词】
：
GENE transfer GENE therapy human CLOTTING factor Ⅸ cell-collagen INJECTION expre 
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In this study, rabbits were used as a model for gene therapy for hemophilia B, Human factor Ⅸ cDNA was transferred to cultured normal rabbit skin fibroblasts (RSF) by a recombinant plasmid (pCMVIX) or retrovirus(XL-IX or N2CMVIX) constructed in our labora
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