本文用组织化学方法,选择能反映血管壁糖代谢3个途径及平滑肌能量利用的5个关键酶,在同一显微镜下对正常SD系不同月龄组大鼠海马血管的酶代谢进行了半定量研究。结果为乳酸脱氢酶活性随着大鼠月龄及血管口径的增加而增强,琥珀酸脱氢酶及细胞色素氧化酶示轻度反应,葡萄糖—6—磷酸脱氢酶呈轻度至中度活性,钙激活三磷酸腺苷酶在动脉及微动脉示极强阳性,静脉示强阳性,毛细血管呈中度至强阳性。讨论了海马血管壁代谢酶的变化与海马血管病的关系。 In this paper, we used histochemical methods to select five key enzymes that reflect the glucose metabolism in the vascular wall and the energy utilization of smooth muscle. Semiquantitative studies were performed on the enzymatic metabolism of hippocampal blood vessels in normal SD rats of different age groups under the same microscope . The results showed that lactate dehydrogenase activity increased with age and blood vessel diameter of rats increased, succinate dehydrogenase and cytochrome oxidase showed mild reaction, glucose-6-phosphate dehydrogenase showed mild to moderate Activity, calcium-activated adenosine triphosphate in the arterial and arteriolar showed extremely strong positive vena cava strong, moderate to strong positive capillary. The relationship between changes of vascular wall metabolic enzymes and hippocampal vascular diseases in hippocampus was discussed.