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干扰素是目前治疗乙肝、丙肝唯一有效的抗病毒药物,为了使肝炎患者对其有比较清楚的认识,帮助他们决定是否选择干扰素治疗,了解在治疗过程中应注意的问题等。我们谈以下几个问题。 干扰素治疗的适应症 慢性乙型肝炎患者血清病毒标志物(HBeAg,HBV DNA)阳性,慢性丙型肝炎患者血清病毒标志物(抗—HCV.HCV RNA)阳性,均可试用干扰素治疗。但最好同时符合下述条件:血清丙氨酸转氨酶(ALT)持续轻度增高(100—300单位/升),无重要合并症,肝组织病理检查有炎症活动而无
Interferon is currently the only effective antiviral drug for hepatitis B and C treatment. In order to make patients with hepatitis have a clearer understanding of it, they can help them decide whether to choose interferon treatment or not, and understand the problems they should pay attention to in the course of treatment. We talk about the following questions. Interferon therapy indications Serum viral markers (HBeAg, HBV DNA) positive in patients with chronic hepatitis B, serum viral markers (anti-HCV. HCV RNA) positive in patients with chronic hepatitis C, can try interferon treatment. But it is best to meet the following conditions at the same time: Serum alanine aminotransferase (ALT) sustained mild increase (100-300 units / liter), no significant complications, liver histopathology with inflammatory activity and no