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肾病是我国常见的肾小球疾病，病理类型很多，但膜型ＩｇＡ肾病极罕见。本文报告３例膜型ＩｇＡ肾病。病理特点是系膜增生的同时，肾小球毛细血管基底膜增厚，并有钉突形成。患者有大量蛋白尿。系膜区有大量ＩｇＡ沉积，毛细血管基底膜外侧有ＩｇＧ沉积。超微结构显示在系膜区及基底膜上皮细胞下均有电子致密物。本文通过免疫荧光和免疫电镜的研究认为，膜型ＩｇＡ肾病是膜型肾小球肾炎与系膜增生型ＩｇＡ肾病的相互重叠。
Kidney disease is a common glomerular disease in our country, many pathological types, but very rare membranous IgA nephropathy. This article reports 3 cases of membranous IgA nephropathy. Pathological features of mesangial proliferation at the same time, glomerular capillary basement membrane thickening, and nail formation. Patients have a lot of proteinuria. Mesangial area has a large number of IgA deposition, capillary basement membrane with IgG deposition outside. Ultrastructure showed electron-dense material under the mesangial and basement membrane epithelial cells. In this paper, immunofluorescence and immunoelectron microscopy studies suggest that membranous IgA nephropathy is membranous glomerulonephritis and mesangial proliferative IgA nephropathy overlap.