论文部分内容阅读
吸宫术前机械性地扩张宫颈是困难的,特别是初孕妇。可因此导致宫颈组织及附近结构的损伤.据报道这种损伤的发生率在0.4～4%之间。宫颈损伤的严重后果是在再次妊娠时能导致中期妊娠流产和早产。天然前列腺素用于术前促宫颈变软虽然有效,但由于胃肠道副作用发生率高以及给药与宫颈充分扩张之间间隔时间长而限制了其应用。已合成了一系列前列腺素类似物试图使宫颈扩张迅速而副作用少的剂型。最近已研制出阴道栓剂含1mg Geme-
Suction before the mechanical expansion of the cervix is difficult, especially early pregnant women. May result in damage to the cervical tissue and nearby structures, and the incidence of this injury is reported to be between 0.4 and 4%. Serious consequences of cervical injury in pregnancy can lead to miscarriage and premature birth in the second trimester. Natural prostaglandins for preoperative cervical stimulation of the soft though effective, but because of the high incidence of gastrointestinal side effects and administration and cervical full expansion of the interval between a long time limit its application. A series of prostaglandin analogues have been synthesized that attempt to rapidly expand the cervix with few side effects. Recently, pessaries have been developed containing 1mg Geme-