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目的初步了解山西省部分地区、部分人群丙型肝炎病毒(HCV)感染分布特点。方法采用查阅文献与描述性流行病学、实验室检测相结合的方法,对山西省HIV感染者、既往有偿采供血人员、无偿献血人群的HCV感染特点进行初步调查分析。结果山西省160例HIV感染者中检出HCV阳性111例,其中男性97例(60.6%),女性14例(8.75%)。2 875例既往有偿采供血人员中,检出HCV阳性500例,其中男性298例(10.37%),女性202例(7.03%)。1 496例无偿献血人群中共检出HCV阳性5例,其中男性3例(0.2%),女性2例(0.13%)。结论有吸毒史的HIV感染者及既往有偿采供血人员是丙型肝炎的高危人群,由于目前对丙型肝炎的治疗既缺乏有效手段,又没有特异的疫苗。因此,保障安全用血,对高危人群加强宣传教育,做好防治工作,是阻断HCV传播的主要方法。
Objective To understand the distribution of hepatitis C virus (HCV) infection in some areas of Shanxi Province. Methods According to the literature review, combined with descriptive epidemiology and laboratory tests, the characteristics of HCV infection in HIV-infected persons, former paid blood donors and non-compensated blood donors in Shanxi Province were investigated. Results A total of 111 HCV positive cases were detected in 160 cases of HIV infection in Shanxi Province, including 97 males (60.6%) and 14 females (8.75%). Of the 2,875 previously paid blood donors, 500 were positive for HCV, of which 298 (10.37%) were male and 202 (7.03%) were female. Among the 496 unpaid blood donors, 5 were positive for HCV, including 3 males (0.2%) and 2 females (0.13%). Conclusion HIV-infected persons with history of drug addiction and former paid-for blood donors are at high risk of hepatitis C. Due to the current lack of effective means to treat hepatitis C, there is no specific vaccine. Therefore, to ensure safe blood use, to strengthen publicity and education on high-risk groups and to prevent and control them is the main method of blocking the spread of HCV.