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近年来间质-上皮相互作用机制在良性前列腺增生症(benign prostatic hyperplasia,BPH)发病中的作用受到人们的重视。其中,起关键作用的是多肽生长因子和细胞外基质(extracellular matrix,ECM)。碱性成纤维细胞生长因子(basic fibroblast groth factor,BFGF)是前列腺组织中主要生长因子,在BPH发病中的重要作用已为人们所认识,但对于其详细作用以及与细胞外基质之间关系,人们目前了解甚少。笔者
In recent years, the role of the interstitial-epithelium interaction mechanism in the pathogenesis of benign prostatic hyperplasia (BPH) has received much attention. Among them, play a key role in the polypeptide growth factor and extracellular matrix (extracellular matrix (ECM). Basic fibroblast growth factor (basic fibroblast groth factor, BFGF) is a major growth factor in prostate tissue, and its important role in the pathogenesis of BPH has been well recognized. However, its detailed function and its relationship with the extracellular matrix, People do not know much about it right now. author