近年来许多研究证实丘脑与痛觉的关系密切。我们曾在丘脑束旁核内同时记录到痛兴奋和痛抑制神经元的放电。还有报导中脑网状结构细胞对伤害性刺激也出现兴奋效应和抑制效应。电刺激中央灰质可影响束旁核痛敏和痛抑制神经元的活动。这些工作为阐明痛觉的产生机制及中枢对伤害性信息的整合作用提供了依据。但是,中枢其它核团中痛兴奋和痛抑制神经元是否也同时活动,不同水平两个核团中的痛兴奋和痛抑制神经元的活动在机能上有无联系以及电 In recent years, many studies confirm that the thalamus and pain are closely related. We have recorded both painful and pain-suppressing neuronal discharges in the paraventricular nucleus of the thalamus. It has also been reported that midbrain reticular cells also exhibit excitatory and inhibitory effects on noxious stimuli. Electrical stimulation of central gray matter can affect parainfluency and pain inhibition of neuronal activity. These works provide the basis for elucidating the mechanism of pain and the central role of integrating harmful information. However, whether pain-stimulating and pain-suppressing neurons in other nuclei in the central nucleus also act simultaneously, pain excitement and pain at two different levels of nucleus depress neuronal activity in terms of their functional connection