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健康雄性杂种狗从股动脉放血,使动脉血压降至40mmHg,并维持于此水平达60min,动脉及混合静脉血中6-酮-前列腺素F_(1α)含量分别从失血前834±481,825±333增至1558±588,2066±833pg/ml(X±SE,P<0.05);血浆总钙从9.09±0.83降为7.96±1.29,而血镁从3.98±0.82增至4.45±0.87mg/dl(X±SE,P均<0.01);全血维生素C从0.39±0.13增至0.46±0.18mg/dl(X±SE,P<0.05)。本文简要讨论了这些病理生化改变的意义。
Healthy male mongrel dogs were bled from the femoral artery and the arterial blood pressure was decreased to 40mmHg and maintained at this level for 60min. The contents of 6-keto-prostaglandin F_ (1α) in arteries and mixed venous blood decreased from 834 ± 481, 825 ± 333 To 1558 ± 588 and 2066 ± 833 pg / ml (X ± SE, P <0.05). The total plasma calcium decreased from 9.09 ± 0.83 to 7.96 ± 1.29 and the blood magnesium increased from 3.98 ± 0.82 to 4.45 ± 0.87 mg / dl X ± SE, P <0.01, respectively). Whole blood vitamin C increased from 0.39 ± 0.13 to 0.46 ± 0.18 mg / dl (X ± SE, P <0.05). This article briefly discusses the significance of these pathological and biochemical changes.