This paper investigated the applicability and effects of infrared reflective coating on energy con-sumption of factory building in hot summer and warm winter zone. It first resorted to theoretical calculation, which demonstrated the beneficial effects of infrared reflective coating on reducing building energy consumption. Then it analyzed a field measurement done on two identical rooms respectively with ordinary coated roof and in-frared reflective coated roof from November 2006 to October 2007, on a 24h basis. The measured data include exterior and interior roof surface temperature, indoor air temperature, and indoor globe temperature. The relat-ed weather data is from a weather station near the measured area. The continuous measurement has been accom-plished in southern China, and the measured data indicate that roof surface temperature and heat gain are signifi-cantly decreased in summer while slight negative effects in winter are induced by adopting infrared reflective coating. Thus it is simple and applicable to reduce building energy consumption in this area by applying infrared reflective coating. Regress equation between reduced roof thermal property, such as surface temperature and heat gain, and reduction in absorbed solar radiation shows their highly linear relationship. Based on the mea-sured data, it is estimated that the reduced power consumption is 3.45 kWh/m2·month in June.