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目的探讨体部伽玛刀治疗肝脏转移瘤的方法和近期疗效。方法肝脏转移瘤病人46例,根据肿瘤的位置、临床靶体积、病人的身体状况与治疗目的,制定治疗计划,伽玛刀治疗方案采用分次立体定向放射治疗(FSRT),计划靶体积边缘剂量4.0~6.0Gy/次,50%~85%等剂量曲线包绕,3~5次/周,共治疗6~13次。结果治疗后1~3个月影像学复查肿瘤消失7例(15.2%),缩小31例(67.4%),无变化8例(17.4%),增大0例,有效率82.6%。无放射性肝炎等严重治疗反应发生。结论体部伽玛刀治疗肝脏转移瘤近期疗效确切,毒副反应小,可明显改善病人的生存质量。
Objective To explore the method and short-term curative effect of body gamma knife in the treatment of liver metastases. Methods Forty-six patients with liver metastases were enrolled in this study. According to the location of the tumor, clinical target volume, the patient’s physical condition and the purpose of the treatment, a treatment plan was formulated. The gamma knife treatment consisted of fractionated stereotactic radiation therapy (FSRT) 4.0 ~ 6.0Gy / times, 50% ~ 85% isodose curve wrap, 3 ~ 5 times / week, a total of 6 to 13 times. Results The tumors disappeared in 7 cases (15.2%), reduced in 31 cases (67.4%), unchanged in 8 cases (17.4%), increased in 0 cases and achieved an effective rate of 82.6%. Radiation-free hepatitis and other serious treatment response. Conclusion Gamma knife treatment of liver metastases recent curative effect, toxicity is small, can significantly improve the quality of life of patients.